4-Morpholinoacetophenone → 2-Bromo-1-(4-morpholinophenyl)ethanone

HRID 10785

Reaction equation

[N:1]1([C:7]2[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][CH:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Br:16]CC(C1C=CC(N2CCCCC2)=CC=1)=O>>[Br:16][CH2:14][C:13]([C:10]1[CH:9]=[CH:8][C:7]([N:1]2[CH2:6][CH2:5][O:4][CH2:3][CH2:2]2)=[CH:12][CH:11]=1)=[O:15]

Participants

Reactant 2

HCID 383624-Morpholinoacetophenone

HCID 158645462-Bromo-1-(4-(piperidin-1-yl)phenyl)ethanone

Product 1

HCID 27953572-Bromo-1-(4-morpholinophenyl)ethanone

Procedure

This compound was prepared from 1-[4-(4-morpholinyl)phenyl]ethanone (Aldrich) by procedures analogous to those used to prepare 2-bromo-1-[4-(1-piperidinyl)phenyl]ethanone (Example 7).

Sources & evidence

ORD record: ord-73931fa5a60e46348d2c319123fbab8b
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07094896B2

Linked notes

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