HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Nitrophenyl)-1-piperazinepropanol → 4-(3-Hydroxypropyl)-1-(4-isothiocyanatophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Nitrophenyl)-1-piperazinepropanol | HCID 21958933 | — |
| Reactant | HCID 178418790 | HCID 178418790 | — |
| Product | 4-(3-Hydroxypropyl)-1-(4-isothiocyanatophenyl)piperazine | HCID 9965439 | — |
Reaction Steps
This compound was prepared from 4-(4-nitrophenyl)-1-piperazinepropanol (which can be prepared according to the procedure of Loewe and Mieth Arzneim.-Forsch. 1966, 16, 1306–1310) using the hydrogenation and isothiocyanate-forming reactions used in Example 4. MS (ES) MH+=277.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07094896B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-73aec980c739465dae1d7432720481ad |
| Source note | uspto-grants-2006_08 |