2-Propylvaleryl chloride → HCID 86750062, compound

HRID 1081249

Reaction equation

HRID 1081249 reaction equation
[C:1](Cl)(=[O:9])[CH:2]([CH2:6][CH2:7][CH3:8])[CH2:3][CH2:4][CH3:5].Cl.[NH2:12][CH:13]([C:18]([NH2:20])=[O:19])[CH2:14][CH:15]([CH3:17])[CH3:16]>>[CH2:3]([CH:2]([CH2:6][CH2:7][CH3:8])[C:1]([NH:20][C:18](=[O:19])[C@H:13]([CH2:14][CH:15]([CH3:17])[CH3:16])[NH2:12])=[O:9])[CH2:4][CH3:5]

Participants

3

Reactant 2

HCID 762402-Propylvaleryl chlorideHCID 128663002-Amino-4-methylpentanamide hydrochloride

Product 1

HCID 86750062HCID 86750062, compound

Procedure

The title compound was prepared from valproyl chloride (2.0 g, 12.3 mmole) and DL-leucinamide hydrochloride (2.0 g, 12.05 mmole), according to the procedure described in Ex. 1. 2.36 g (9.2 mmole, 76%) of a white crystalline solid, mp 151°-2° C., was thus obtained.

Sources & evidence

ORD record
ord-599748f41df843c7b888767f1e693cd2
Source dataset
uspto-grants-1996_12
Patent number
US05585358

Linked notes

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