Sodium ion → 5-[4-(5-Fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylamino]quinoline

HRID 108143

Reaction equation

HRID 108143 reaction equation
[BH4-:44].[F:12][c:13]1[cH:14][c:15]([C:22]([CH2:23][C:24]([CH:25]=[N:26][c:27]2[c:28]3[cH:29][cH:30][cH:31][n:32][c:33]3[cH:34][cH:35][cH:36]2)([C:37]([F:38])([F:39])[F:40])[OH:41])([CH3:42])[CH3:43])[c:16]2[c:17]([cH:21]1)[CH2:18][CH2:19][O:20]2.[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][n:11]2.[Na+:45]>>[F:12][c:13]1[cH:14][c:15]([C:22]([CH2:23][C:24]([CH2:25][NH:26][c:27]2[c:28]3[cH:29][cH:30][cH:31][n:32][c:33]3[cH:34][cH:35][cH:36]2)([C:37]([F:38])([F:39])[F:40])[OH:41])([CH3:42])[CH3:43])[c:16]2[c:17]([cH:21]1)[CH2:18][CH2:19][O:20]2

Participants

5

Reactant 4

HCID 923Sodium ionHCID 119115-AminoquinolineHCID 28123BorohydrideHCID 68851814HCID 68851814, compound

Product 1

HCID 115759705-[4-(5-Fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylamino]quinoline

Sources & evidence

ORD record
ord-28d2ee98388a4059a98a91fa518112e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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