Acetic Acid → 8-(3,5-Dimethyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

HRID 108144

Reaction equation

HRID 108144 reaction equation
[C:1]([OH:2])(=[O:3])[CH3:4].[CH3:27][c:28]1[n:29][o:30][c:31]([CH3:37])[c:32]1[S:33](=[O:34])(=[O:35])[Cl:36].[F:5][C:6]([O:7][c:8]1[cH:9][cH:10][c:11]([N:14]2[C:15](=[O:24])[C:16]3([CH2:17][CH2:18]2)[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]3)[cH:12][cH:13]1)([F:25])[F:26]>>[F:5][C:6]([O:7][c:8]1[cH:9][cH:10][c:11]([N:14]2[C:15](=[O:24])[C:16]3([CH2:17][CH2:18]2)[CH2:19][CH2:20][N:21]([S:33]([c:32]2[c:28]([CH3:27])[n:29][o:30][c:31]2[CH3:37])(=[O:34])=[O:35])[CH2:22][CH2:23]3)[cH:12][cH:13]1)([F:25])[F:26]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 27363193,5-Dimethylisoxazole-4-sulfonyl chlorideHCID 667427592-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one

Product 1

HCID 595779878-(3,5-Dimethyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

Sources & evidence

ORD record
ord-354c7d9f342c40fcb77a40c67bff17fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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