4-(Octyloxy)benzoic acid → 4-Octyloxybenzoyl chloride
Reaction equation
[CH2:1]([O:9][C:10]1[CH:18]=[CH:17][C:13]([C:14](O)=[O:15])=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].P(Cl)(Cl)(Cl)(Cl)[Cl:20]>C1C=CC=CC=1>[CH2:1]([O:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]([Cl:20])=[O:15])=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2.78 g of 4-octyloxybenzoic acid was added to 10 ml of benzene, and under stirring at room temperature, 2.36 g of PCl5 was added little by little. The mixture was then heated under reflux for 4 hours. Thereafter, the solvent was distilled off to obtain 4-octyloxybenzoic acid chloride.
Workup
- temperatureThe mixture was then heated
- temperatureunder reflux for 4 hours
- distillationThereafter, the solvent was distilled off
Sources & evidence
- ORD record
- ord-d0c650b3ad4245688f41bd261bc78567
- Source dataset
- uspto-grants-1991_07
- Patent number
- US05034152
Reaction notes
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