2-(1,4-Dioxaspiro[4.5]decan-8-ylidene)acetonitrile → 1,4-Dioxaspiro[4.5]decane-8-acetonitrile
Reaction equation
[C:1]([CH:3]=[C:4]1[CH2:13][CH2:12][C:7]2([O:11][CH2:10][CH2:9][O:8]2)[CH2:6][CH2:5]1)#[N:2]>C(O)C.[Pt]=O>[C:1]([CH2:3][CH:4]1[CH2:13][CH2:12][C:7]2([O:8][CH2:9][CH2:10][O:11]2)[CH2:6][CH2:5]1)#[N:2]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
The above nitrile (2.15 g) is treated with platinum oxide (0.1 g) in ethanol (200 ml) and hydrogenated at 3 atmospheres pressure over 4 hours. Removal of the catalyst and concentration of the solvent gives 8-cyanomethyl-1,4-dioxaspiro[4.5]decane as an oil.
Workup
- customRemoval of the catalyst and concentration of the solvent
Sources & evidence
- ORD record
- ord-20b26b7cc5964f09a5be810b2bb97fa7
- Source dataset
- uspto-grants-1991_07
- Patent number
- US05034381
Reaction notes
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