Sodium Carbonate → 2,2'-Thiodipyridine

HRID 1088029

Reaction equation

HRID 1088029 reaction equation
[S:1]([O-])(=O)(=O)[CH3:2].S[C:7]1[CH:12]=[CH:11][N:10]=[CH:9][CH:8]=1.C(=O)([O-])[O-].[Na+].[Na+]>>[N:10]1[CH:11]=[CH:12][CH:7]=[CH:8][C:9]=1[S:1][C:2]1[CH:12]=[CH:7][CH:8]=[CH:9][N:10]=1

Participants

4

Reactant 3

HCID 10340Sodium CarbonateHCID 85257MethanesulfonateHCID 178418431pyridine-4-thiol

Product 1

HCID 5211142,2'-ThiodipyridineYield 71%

Procedure

This product (4) is treated with 4-mercaptopyridine (2.45 g; 1.3 equivalents) and sodium carbonate (1.8 g; 1 equivalents) at room temperature for 2 hours to give 4-pyridyl sulfide (7) (7.87 g) as in Example F-2. Yield: 71%.

Sources & evidence

ORD record
ord-10208178e5124345932ac7935c25e228
Source dataset
uspto-grants-1990_10
Patent number
US04960879

Linked notes

Loading…