2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile → 1-({2-[3,5-bis(Trifluoromethyl)phenyl]-1,3-oxazol-4-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 108925

Reaction equation

HRID 108925 reaction equation
[CH3:1][c:2]1[nH:3][c:4]2[cH:5][cH:6][c:7]([C:15]#[N:16])[c:8]([C:11]([F:12])([F:13])[F:14])[c:9]2[cH:10]1.[F:17][C:18]([c:19]1[cH:20][c:21](-[c:29]2[o:30][cH:31][c:32]([CH2:34][Cl:35])[n:33]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[cH:24]1)([F:36])[F:37]>>[CH3:1][c:2]1[n:3]([CH2:34][c:32]2[cH:31][o:30][c:29](-[c:21]3[cH:20][c:19]([C:18]([F:17])([F:36])[F:37])[cH:24][c:23]([C:25]([F:26])([F:27])[F:28])[cH:22]3)[n:33]2)[c:4]2[cH:5][cH:6][c:7]([C:15]#[N:16])[c:8]([C:11]([F:12])([F:13])[F:14])[c:9]2[cH:10]1

Participants

3

Reactant 2

HCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 578004682-[3,5-Bis(trifluoromethyl)phenyl]-4-(chloromethyl)-1,3-oxazole

Product 1

HCID 866207131-({2-[3,5-bis(Trifluoromethyl)phenyl]-1,3-oxazol-4-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-8b27a331466b45ac9e9b1bc2d7155cc8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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