Methanesulfonyl chloride → Methyl 2-[4-(Methylsulfonamido)phenyl]acetate
Reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[CH:4][CH:3]=1.[CH3:13][S:14](Cl)(=[O:16])=[O:15]>N1C=CC=CC=1>[CH3:13][S:14]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[CH:6][CH:7]=1)(=[O:16])=[O:15]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
In a manner similar to preparation 3, react 4-aminobenzeneacetic acid, methyl ester with methanesulfonyl chloride, and pyridine to obtain the title compound.
Workup
- customIn a manner similar to preparation 3
Sources & evidence
- ORD record
- ord-9e8f09d67a16466dafcc43a39ea723f4
- Source dataset
- uspto-grants-1990_10
- Patent number
- US04966967
Reaction notes
Loading…