1,2-Dibromoethane → 2-(2-Bromoethoxy)-1,3-dichloro-5-methylbenzene

HRID 1092791

Reaction equation

HRID 1092791 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([OH:9])=[C:4]([Cl:10])[CH:3]=1.[Br:11][CH2:12][CH2:13]Br>>[Br:11][CH2:12][CH2:13][O:9][C:5]1[C:6]([Cl:8])=[CH:7][C:2]([CH3:1])=[CH:3][C:4]=1[Cl:10]

Participants

3

Reactant 2

HCID 78391,2-DibromoethaneHCID 170772,6-Dichloro-4-methylphenol

Product 1

HCID 665901782-(2-Bromoethoxy)-1,3-dichloro-5-methylbenzeneYield 61%

Procedure

4-Methyl-2,6-dichlorophenol was reacted with 1,2-dibromoethane according to the procedure described in Step 2A to yield the titled compound (4.66 g, 61%). 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 2.29 (s, 3H) 3.70 (d, J=7.20 Hz, 2H) 4.29 (d, J=7.20 Hz, 2H) 7.11 (s, 2H).

Sources & evidence

ORD record
ord-308e9e16240d4373893427ead1a1fda6
Source dataset
uspto-grants-2012_03
Patent number
US08129538B1

Linked notes

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