1-Methyl-2-imidazolecarboxaldehyde → 6-[2-(3-chloro-4-methoxyphenyl)ethyl]-6-cyclopentyl-3-[(1-methyl-1H-imidazol-2-yl)methyl]dihydro-2H-pyran-2,4(3H)-dione

HRID 110189

Reaction equation

HRID 110189 reaction equation
[CH3:1][n:2]1[c:3]([CH:7]=[O:8])[n:4][cH:5][cH:6]1.[CH3:9][c:10]1[cH:11][c:12]([CH3:13])[n:14]2[n:15][c:16]([CH:17]=[O:18])[n:19][c:20]2[n:21]1.[Cl:22][c:23]1[cH:24][c:25]([CH2:31][CH2:32][C:33]2([CH:41]3[CH2:42][CH2:43][CH2:44][CH2:45]3)[CH2:34][C:35](=[O:40])[CH2:36][C:37](=[O:39])[O:38]2)[cH:26][cH:27][c:28]1[O:29][CH3:30].[Cl:46][c:47]1[cH:48][c:49]([CH2:50][CH2:51][C:52]2([CH:53]3[CH2:54][CH2:55][CH2:56][CH2:57]3)[O:58][C:59](=[O:60])[CH2:61][C:62](=[O:63])[CH2:64]2)[cH:65][cH:66][c:67]1[O:68][CH:69]([CH3:70])[CH3:71]>>[CH3:1][n:2]1[c:3]([CH2:7][CH:36]2[C:35](=[O:40])[CH2:34][C:33]([CH2:32][CH2:31][c:25]3[cH:24][c:23]([Cl:22])[c:28]([O:29][CH3:30])[cH:27][cH:26]3)([CH:41]3[CH2:42][CH2:43][CH2:44][CH2:45]3)[O:38][C:37]2=[O:39])[n:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 1395751-Methyl-2-imidazolecarboxaldehydeHCID 160761096-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-dihydro-3H-pyran-2,4-dioneHCID 167287396-[2-(3-Chloro-4-isopropoxy-phenyl)ethyl]-6-cyclopentyl-tetrahydropyran-2,4-dioneHCID 236352265,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbaldehyde

Product 1

HCID 498712296-[2-(3-chloro-4-methoxyphenyl)ethyl]-6-cyclopentyl-3-[(1-methyl-1H-imidazol-2-yl)methyl]dihydro-2H-pyran-2,4(3H)-dione

Sources & evidence

ORD record
ord-3996a75cb4214350a13b76e461ec96e0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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