3-Bromobenzoic acid → 3-bromo-N-[[3-[5-(3-chlorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-3-azabicyclo[3.1.0]hexan-2-yl]methyl]benzamide

HRID 110525

Reaction equation

HRID 110525 reaction equation
[Br:24][c:25]1[cH:26][c:27]([C:28](=[O:29])[OH:30])[cH:31][cH:32][cH:33]1.[NH2:1][CH2:2][CH:3]1[CH:4]2[CH2:5][CH:6]2[CH2:7][N:8]1[C:9](=[O:10])[c:11]1[n:12][c:13]([CH3:23])[s:14][c:15]1-[c:16]1[cH:17][c:18]([Cl:22])[cH:19][cH:20][cH:21]1>>[NH:1]([CH2:2][CH:3]1[CH:4]2[CH2:5][CH:6]2[CH2:7][N:8]1[C:9](=[O:10])[c:11]1[n:12][c:13]([CH3:23])[s:14][c:15]1-[c:16]1[cH:17][c:18]([Cl:22])[cH:19][cH:20][cH:21]1)[C:28]([c:27]1[cH:26][c:25]([Br:24])[cH:33][cH:32][cH:31]1)=[O:29]

Participants

3

Reactant 2

HCID 114563-Bromobenzoic acidHCID 68442716[2-(Aminomethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-[5-(3-chlorophenyl)-2-methyl-1,3-thiazol-4-yl]methanone

Product 1

HCID 684439793-bromo-N-[[3-[5-(3-chlorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-3-azabicyclo[3.1.0]hexan-2-yl]methyl]benzamide

Sources & evidence

ORD record
ord-f76df84f20894224aca6a5c1c70074cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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