3-Pyrrolidinemethanamine,N-cyclopropyl-4-fluoro-,(3R,4S)-(9CI) → 7-[3-[(Cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluorocyclopropyl)-4-oxo-1,8-naphthyridine-3-carboxylic acid

HRID 110546

Reaction equation

HRID 110546 reaction equation
[CH:21]1([NH:24][CH2:25][CH:26]2[CH2:27][NH:28][CH2:29][CH:30]2[F:31])[CH2:22][CH2:23]1.[Cl:1][c:2]1[c:3]([F:20])[cH:4][c:5]2[c:6](=[O:19])[c:7]([C:16](=[O:17])[OH:18])[cH:8][n:9]([CH:12]3[CH:13]([F:15])[CH2:14]3)[c:10]2[n:11]1>>[c:2]1([N:28]2[CH2:27][CH:26]([CH2:25][NH:24][CH:21]3[CH2:22][CH2:23]3)[CH:30]([F:31])[CH2:29]2)[c:3]([F:20])[cH:4][c:5]2[c:6](=[O:19])[c:7]([C:16](=[O:17])[OH:18])[cH:8][n:9]([CH:12]3[CH:13]([F:15])[CH2:14]3)[c:10]2[n:11]1

Participants

3

Reactant 2

HCID 230620733-Pyrrolidinemethanamine,N-cyclopropyl-4-fluoro-,(3R,4S)-(9CI)HCID 233720907-Chloro-6-fluoro-1-(2-fluorocyclopropyl)-4-oxo-1,8-naphthyridine-3-carboxylic acid

Product 1

HCID 231256717-[3-[(Cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluorocyclopropyl)-4-oxo-1,8-naphthyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-2224c61d8ddc4b64aae7467e04beee35
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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