Benzenemethanol, 2,6-dichloro- → 1-(2-Butenyl)-7-(2,6-dichlorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine

HRID 1107777

Reaction equation

HRID 1107777 reaction equation
[CH2:1]([N:5]1[C:9]2=[C:10](Cl)[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4].[Cl:17][C:18]1[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[C:19]=1[CH2:20][OH:21]>>[CH2:1]([N:5]1[C:9]2=[C:10]([O:21][CH2:20][C:19]3[C:18]([Cl:17])=[CH:25][CH:24]=[CH:23][C:22]=3[Cl:26])[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4]

Participants

3

Reactant 2

HCID 27156Benzenemethanol, 2,6-dichloro-HCID 537196241-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine

Product 1

HCID 545035521-(2-Butenyl)-7-(2,6-dichlorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazineYield 83.5%

Procedure

The title compound (cis/trans=21:79) was prepared as a pale yellow powder in 83.5% yield in a similar procedure to that described in Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=24/76) and 2,6-dichlorobenzyl alcohol.

Sources & evidence

ORD record
ord-a1fa01ac0e87449c974144d55ba80d6c
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Linked notes

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