Acetanilide → 4-Nitroacetanilide

HRID 1108872

Reaction equation

[C:1]([NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[N+:11]([O-])([OH:13])=[O:12].S(=O)(=O)(O)O>>[CH3:2][C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][CH:6]=1)=[O:3]

Participants

Reactant 3

HCID 904Acetanilide

HCID 944Nitric Acid

HCID 1118Sulfuric Acid

Product 1

HCID 76914-Nitroacetanilide

Procedure

nitrating acetanilide using a mixture of nitric acid and sulfuric acid to produce 4-nitroacetanilide and nitrating further using a mixture of nitric acid and sulfuric acid to produce VI;

Sources & evidence

ORD record: ord-72d61edbfb594a8f9bc7f6f7920b9737
Source dataset: uspto-grants-2000_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06069277

Linked notes

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