5-(Difluoromethoxy)-2-methylbenzoic acid → 2-(1-{[5-(Difluoromethoxy)-2-methylphenyl]carbonyl}piperidin-4-yl)-5-(7-methoxy-3H-spiro[1-benzofuran-2,1'-cyclopentan]-4-yl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

Reaction equation

[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:16]2=[N:20][N:19]([CH:21]3[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]3)[C:18](=[O:27])[C:17]2([CH3:28])[CH3:29])[c:7]2[c:11]1[O:10][C:9]1([CH2:8]2)[CH2:12][CH2:13][CH2:14][CH2:15]1.[F:30][CH:31]([O:32][c:33]1[cH:34][cH:35][c:36]([CH3:42])[c:37]([C:38](=[O:39])[OH:40])[cH:41]1)[F:43]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:16]2=[N:20][N:19]([CH:21]3[CH2:22][CH2:23][N:24]([C:38]([c:37]4[c:36]([CH3:42])[cH:35][cH:34][c:33]([O:32][CH:31]([F:30])[F:43])[cH:41]4)=[O:39])[CH2:25][CH2:26]3)[C:18](=[O:27])[C:17]2([CH3:28])[CH3:29])[c:7]2[c:11]1[O:10][C:9]1([CH2:8]2)[CH2:12][CH2:13][CH2:14][CH2:15]1