Potassium Cation → 2-(2-Fluoroethyl)-6-(methyloxy)-7-nitro-1,2,3,4-tetrahydroisoquinoline

HRID 111028

Reaction equation

[C:20](=[O:21])([O-:22])[O-:23].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][c:12]1[N+:13](=[O:14])[O-:15])[CH2:9][NH:8][CH2:7][CH2:6]2.[CH3:26][C:27]#[N:28].[I:16][CH2:17][CH2:18][F:19].[K+:24].[K+:25]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][c:12]1[N+:13](=[O:14])[O-:15])[CH2:9][N:8]([CH2:17][CH2:18][F:19])[CH2:7][CH2:6]2

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 6342Acetonitrile

HCID 19660Carbonate Ion

HCID 69804Ethane, 1-fluoro-2-iodo-

HCID 594418746-Methoxy-7-nitro-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 594418432-(2-Fluoroethyl)-6-(methyloxy)-7-nitro-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record: ord-03ff443b04bf411c875a6147468d370b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Linked notes

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