2-Chloro-5-(trifluoromethyl)pyridine → 4-(3-Chloro-5-trifluoromethyl-2-pyridyloxy)phenoxypropionic acid chloride hydrochloride
Reaction equation
[Cl:1]C1C=CC(C(F)(F)F)=CN=1.[ClH:12].[F:13][C:14]([F:35])([F:34])[C:15]1[CH:16]=[CH:17][C:18]([O:21][C:22]2[CH:33]=[CH:32][C:25]([O:26][CH:27]([CH3:31])[C:28]([Cl:30])=[O:29])=[CH:24][CH:23]=2)=[N:19][CH:20]=1>BrC(CC)C(O)=O>[ClH:1].[Cl:12][C:17]1[C:18]([O:21][C:22]2[CH:33]=[CH:32][C:25]([O:26][CH:27]([CH3:31])[C:28]([Cl:30])=[O:29])=[CH:24][CH:23]=2)=[N:19][CH:20]=[C:15]([C:14]([F:34])([F:35])[F:13])[CH:16]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
By using 2-chloro-5-trifluoromethylpyridine instead of 2,3-dichloro-5-trifluoromethylpyridine in the above (b), 2-(4-(5-trifluoromethyl-2-pyridyloxy)phenoxy)propionic acid chloride hydrochloride was obtained.