Ethanol → (+/-)-6-Fluoro-8-amino-2,3-dihydrospiro[4H-1-benzopyran-4,5'-thiazolidine]-2',4'-dione

Reaction equation

[CH3:25][CH2:26][OH:27].[CH:21]([Cl:22])([Cl:23])[Cl:24].[F:1][c:2]1[cH:3][c:4]([N+:18]([O-:19])=[O:20])[c:5]2[c:6]([cH:17]1)[C:7]1([CH2:8][CH2:9][O:10]2)[C:11](=[O:16])[NH:12][C:13](=[O:15])[S:14]1.[Pt:28]=[O:29]>>[F:1][c:2]1[cH:3][c:4]([NH2:18])[c:5]2[c:6]([cH:17]1)[C:7]1([CH2:8][CH2:9][O:10]2)[C:11](=[O:16])[NH:12][C:13](=[O:15])[S:14]1

Participants

Reactant 4

HCID 702Ethanol

HCID 6212Chloroform

HCID 82844Platinum oxide (PtO)

HCID 13998517(+/-)-6-fluoro-8-nitro-2,3-dihydrospiro[4H-1-benzopyran-4,5'-thiazolidine]-2',4'-dione

Product 1

HCID 13998518(+/-)-6-Fluoro-8-amino-2,3-dihydrospiro[4H-1-benzopyran-4,5'-thiazolidine]-2',4'-dione

Sources & evidence

ORD record: ord-ed4626ca0df04162b9d0220b134323ea
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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