Ethanol → Sodium 8-aminonaphthalene-1,3,5-trisulfonate

HRID 1112193Notes

Reaction equation

HRID 1112193 reaction equation
[NH2:1][C:2]1[C:11]2[C:10]([S:12]([OH:15])(=[O:14])=[O:13])=[CH:9][C:8]([S:16]([OH:19])(=[O:18])=[O:17])=[CH:7][C:6]=2[C:5]([S:20]([OH:23])(=[O:22])=[O:21])=[CH:4][CH:3]=1.C(O)C.[OH-].[Na+:28]>O>[Na+:28].[Na+:28].[Na+:28].[NH2:1][C:2]1[C:11]2[C:10]([S:12]([O-:15])(=[O:14])=[O:13])=[CH:9][C:8]([S:16]([O-:19])(=[O:17])=[O:18])=[CH:7][C:6]=2[C:5]([S:20]([O-:23])(=[O:22])=[O:21])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 873558-Aminonaphthalene-1,3,5-trisulfonic acid

Product 1

HCID 10343683Sodium 8-aminonaphthalene-1,3,5-trisulfonate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a warm solution of 106.4 g of (80.5%) 8-amino-1,3,5-naphthalenetrisulfonic acid in 100 ml of water and 45.0 ml of 5N sodium hydroxide is slowly added 500 ml of absolute ethanol with vigorous stirring for 30 minutes. The mixture iw cooled to room temperature and filtered. The precipitate is washed with 80% aqueous ethanol, ethanol and ether and is dried in vacuo at 110° C. for 16 hours to give 103.7 g of 8-amino-1,3,5-naphthalenetrisulfonic acid trisodium salt.

Workup

  1. filtrationfiltered
  2. washThe precipitate is washed with 80% aqueous ethanol, ethanol and ether
  3. customis dried in vacuo at 110° C. for 16 hours

Sources & evidence

ORD record
ord-2db68ba84dd24992a29ee26d274a5180
Source dataset
uspto-grants-1978_10
Patent number
US04120891

Reaction notes

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