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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1116Generated: October 23, 2026

Ethanolamine → 16-(2-Hydroxyethylamino)-1-(2-tetrahydropyranyloxy)hexadecane

https://huagongshe.com/en/reaction/1116

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantHexadecanolideHCID 7984—
ReactantDiethanolamineHCID 8113—
ReactantMethyl 16-(2-tetrahydropyranyloxy)hexadecanoateHCID 12687990—
Product16-(2-Hydroxyethylamino)-1-(2-tetrahydropyranyloxy)hexadecaneHCID 19694632—

Reaction Steps

A reaction was conducted in the same manner as in Preparation Example 37 except that ethanolamine and methyl 16-(2-tetrahydropyranyloxy)hexadecanate were used in place of diethanolamine and cyclohexadecanolide, respectively, in Preparation Example 37, thereby obtaining the title compound (IId-4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723497
Source datasetuspto-grants-1998_03
ORD IDord-1fba45c98c28483dbc24abfca08ff922
Source noteuspto-grants-1998_03