3-Aminocinnamic acid ethyl ester → 3-[3-(5-Bromo-2-fluoro-benzoylamino)-phenyl]-acrylic acid ethyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:11])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[CH2:12]([CH3:13])[O:14][C:15]([CH:16]=[CH:17][c:18]1[cH:19][c:20]([NH2:24])[cH:21][cH:22][cH:23]1)=[O:25]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:11])[c:6]([C:7](=[O:9])[NH:24][c:20]2[cH:19][c:18]([CH:17]=[CH:16][C:15]([O:14][CH2:12][CH3:13])=[O:25])[cH:23][cH:22][cH:21]2)[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-14393862f41841c0837e612b35c06e60
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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