Chlorotrimethylsilane → 6-(2-(1H-indazol-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one

Reaction equation

[CH3:35][Si:36]([Cl:37])([CH3:38])[CH3:39].[Cl:1][c:2]1[n:3][c:4]([NH:11][c:12]2[cH:13][c:14]3[c:15]([cH:23][cH:24]2)[O:16][C:17]([CH3:21])([CH3:22])[C:18](=[O:20])[NH:19]3)[c:5]2[c:6]([n:7]1)[nH:8][cH:9][cH:10]2.[NH2:25][c:26]1[cH:27][cH:28][c:29]2[cH:30][n:31][nH:32][c:33]2[cH:34]1>>[c:2]1([NH:25][c:26]2[cH:27][cH:28][c:29]3[cH:30][n:31][nH:32][c:33]3[cH:34]2)[n:3][c:4]([NH:11][c:12]2[cH:13][c:14]3[c:15]([cH:23][cH:24]2)[O:16][C:17]([CH3:21])([CH3:22])[C:18](=[O:20])[NH:19]3)[c:5]2[c:6]([n:7]1)[nH:8][cH:9][cH:10]2