Ethyl 3-oxopyrrolidine-1-carboxylate → 1-Ethoxycarbonyl-3-{5-fluoro-3-[4-(2-methyl1,3-dioxolan-2-yl)phenylthio]phenyl}-3-hydroxypyrrolidine
Reaction equation
[CH2:22]([CH3:23])[O:24][C:25](=[O:26])[N:27]1[CH2:28][C:29](=[O:32])[CH2:30][CH2:31]1.[F:1][c:2]1[cH:3][c:4]([S:9][c:10]2[cH:11][cH:12][c:13]([C:16]3([CH3:21])[O:17][CH2:18][CH2:19][O:20]3)[cH:14][cH:15]2)[cH:5][c:6]([Br:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([S:9][c:10]2[cH:11][cH:12][c:13]([C:16]3([CH3:21])[O:17][CH2:18][CH2:19][O:20]3)[cH:14][cH:15]2)[cH:5][c:6]([C:29]2([OH:32])[CH2:28][N:27]([C:25]([O:24][CH2:22][CH3:23])=[O:26])[CH2:31][CH2:30]2)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-e84a6dd5979b4d2ea9dd561b114dcb7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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