Dichloromethane → 2-Chloro-5-(chloromethyl)-3-methoxypyridine

Reaction equation

[Cl:16][CH2:17][Cl:18].[Cl:1][c:2]1[c:3]([O:10][CH3:11])[cH:4][c:5]([CH2:8][OH:9])[cH:6][n:7]1.[S:12]([Cl:13])([Cl:14])=[O:15]>>[Cl:1][c:2]1[c:3]([O:10][CH3:11])[cH:4][c:5]([CH2:8][Cl:14])[cH:6][n:7]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 59297074(6-Chloro-5-methoxypyridin-3-yl)methanol

Product 1

HCID 592970732-Chloro-5-(chloromethyl)-3-methoxypyridine

Sources & evidence

ORD record: ord-1c0ca4ee1d7b4b868b08e4e1f74b37ce
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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