Ethanol → Nilutamide

Reaction equation

[CH3:1][C:2]1([CH3:9])[C:3](=[O:8])[NH:4][C:5](=[O:7])[NH:6]1.[CH3:24][CH2:25][OH:26].[Cu:27].[N+:10](=[O:11])([O-:12])[c:13]1[c:14]([C:20]([F:21])([F:22])[F:23])[cH:15][c:16]([Cl:19])[cH:17][cH:18]1>>[CH3:1][C:2]1([CH3:9])[C:3](=[O:8])[N:4]([c:16]2[cH:15][c:14]([C:20]([F:21])([F:22])[F:23])[c:13]([N+:10](=[O:11])[O-:12])[cH:18][cH:17]2)[C:5](=[O:7])[NH:6]1

Participants

Reactant 4

HCID 702Ethanol

HCID 6491Dimethylhydantoin

HCID 23978Copper

HCID 670525-Chloro-2-nitrobenzotrifluoride

Product 1

HCID 4493Nilutamide

Sources & evidence

ORD record: ord-2ff1107259c14e8494595fa44057a486
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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