(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone → 1'-{[6-Chloro-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-indol-3-yl]carbonyl}-3H-spiro[2-benzofuran-1,4'-piperidine]

HRID 1123340

Reaction equation

HRID 1123340 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][CH2:18][c:19]5[c:20]4[cH:21][cH:22][cH:23][cH:24]5)[CH2:25][CH2:26]3)[cH:7][nH:8][c:9]2[cH:10]1.[O:27]1[CH2:28][CH2:29][CH:30]([CH2:33][CH2:34][O:35][S:36]([CH3:37])(=[O:38])=[O:39])[CH2:31][CH2:32]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][CH2:18][c:19]5[c:20]4[cH:21][cH:22][cH:23][cH:24]5)[CH2:25][CH2:26]3)[cH:7][n:8]([CH2:33][CH:30]3[CH2:29][CH2:28][O:27][CH2:32][CH2:31]3)[c:9]2[cH:10]1

Participants

3

Reactant 2

HCID 15951937(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanoneHCID 222730832-(Tetrahydro-2H-pyran-4-yl)ethyl methanesulfonate

Product 1

HCID 596576381'-{[6-Chloro-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-indol-3-yl]carbonyl}-3H-spiro[2-benzofuran-1,4'-piperidine]

Sources & evidence

ORD record
ord-7b87041c081e4a4c9bd7f3ca00e949f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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