Dichloromethane → 2-Chloro-8-quinazolinol

Reaction equation

[B:14]([Br:15])([Br:16])[Br:17].[Cl:18][CH2:19][Cl:20].[Cl:1][c:2]1[n:3][c:4]2[c:5]([O:12][CH3:13])[cH:6][cH:7][cH:8][c:9]2[cH:10][n:11]1>>[Cl:1][c:2]1[n:3][c:4]2[c:5]([OH:12])[cH:6][cH:7][cH:8][c:9]2[cH:10][n:11]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 199886952-Chloro-8-methoxyquinazoline

Product 1

HCID 591992302-Chloro-8-quinazolinol

Sources & evidence

ORD record: ord-d5a5363f50cf4253bae0dee9d661ec02
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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