Methanol → 1-(4-Ethylpiperazin-1-yl)-3-(2-hydroxy-2-phenylethyl)isoquinoline

Reaction equation

[BH4-:28].[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([c:9]2[n:10][c:11]([CH2:19][C:20](=[O:21])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[cH:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]23)[CH2:7][CH2:8]1.[CH3:30][OH:31].[Na+:29]>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([c:9]2[n:10][c:11]([CH2:19][CH:20]([OH:21])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[cH:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]23)[CH2:7][CH2:8]1

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium Ion

HCID 28123Borohydride

HCID 225034511-(4-Ethylpiperazin-1-yl)-3-phenacylisoquinoline

Product 1

HCID 225032721-(4-Ethylpiperazin-1-yl)-3-(2-hydroxy-2-phenylethyl)isoquinoline

Sources & evidence

ORD record: ord-21988205d77f4ebf8fb37b2348e9d876
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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