5-Fluoro-6-(4-fluoro-benzylamino)-1,3-dihydro-indol-2-one → 5-[2-(dimethylamino)ethyl]-2-[[5-fluoro-6-[(4-fluorophenyl)methylamino]-2-oxo-1H-indol-3-ylidene]methyl]-3-methyl-1,6,7,8-tetrahydropyrrolo[3,2-c]azepin-4-one
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:18])[c:7]2[c:8]([nH:12][c:13]([CH:16]=[O:17])[c:14]2[CH3:15])[CH2:9][CH2:10][CH2:11]1)[CH3:19].[F:20][c:21]1[cH:22][c:23]2[c:27]([cH:28][c:29]1[NH:30][CH2:31][c:32]1[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]1)[NH:26][C:25](=[O:39])[CH2:24]2>>[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:18])[c:7]2[c:8]([nH:12][c:13]([CH:16]=[C:24]3[c:23]4[cH:22][c:21]([F:20])[c:29]([NH:30][CH2:31][c:32]5[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]5)[cH:28][c:27]4[NH:26][C:25]3=[O:39])[c:14]2[CH3:15])[CH2:9][CH2:10][CH2:11]1)[CH3:19]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8cd5a90ad25d449eb01919429e68e06f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)