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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 112876Generated: October 26, 2026

1,2-Dichloroethane → tert-butyl N-[1-[4-(4-chloro-3-methoxyphenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

https://huagongshe.com/reaction/112876

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
ReactantBoc-DL-valineHCID 270655—
Reactant4-(4-Chloro-3-methoxyphenyl)-3,3-dimethylpiperidin-4-olHCID 57889694—
Producttert-butyl N-[1-[4-(4-chloro-3-methoxyphenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamateHCID 178488266—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-19a331cc8789494b88561837e2302017
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)