Pyridine → 4-bromo-N-[2-chloro-5-(3,5-dimethylpiperazin-1-yl)phenyl]benzenesulfonamide

Reaction equation

[Br:17][c:18]1[cH:19][cH:20][c:21]([S:24](=[O:25])(=[O:26])[Cl:27])[cH:22][cH:23]1.[CH3:1][CH:2]1[CH2:3][N:4]([c:9]2[cH:10][cH:11][c:12]([Cl:16])[c:13]([NH2:14])[cH:15]2)[CH2:5][CH:6]([CH3:8])[NH:7]1.[Cl:28][CH2:29][Cl:30].[n:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[CH3:1][CH:2]1[CH2:3][N:4]([c:9]2[cH:10][cH:11][c:12]([Cl:16])[c:13]([NH:14][S:24]([c:21]3[cH:20][cH:19][c:18]([Br:17])[cH:23][cH:22]3)(=[O:25])=[O:26])[cH:15]2)[CH2:5][CH:6]([CH3:8])[NH:7]1

Participants

Reactant 4

HCID 1049Pyridine

HCID 6344Dichloromethane

HCID 7396p-Bromobenzenesulfonyl chloride

HCID 691968432-Chloro-5-(3,5-dimethylpiperazin-1-yl)aniline

Product 1

HCID 691971624-bromo-N-[2-chloro-5-(3,5-dimethylpiperazin-1-yl)phenyl]benzenesulfonamide

Sources & evidence

ORD record: ord-0c502056fbc1443abf40429e51134e45
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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