1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine → 4-Bromo-6-trifluoromethyl-2-[4-(3-chloro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole

HRID 1129643Notes

Reaction equation

HRID 1129643 reaction equation
[Br:18][c:19]1[cH:20][c:21]([C:29]([F:30])([F:31])[F:32])[cH:22][c:23]2[nH:24][c:25]([Cl:28])[n:26][c:27]12.[Cl:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[Cl:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][N:15]([c:25]3[nH:24][c:23]4[cH:22][c:21]([C:29]([F:30])([F:31])[F:32])[cH:20][c:19]([Br:18])[c:27]4[n:26]3)[CH2:16][CH2:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

3

Reactant 2

HCID 6676191-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazineHCID 115945854-bromo-2-chloro-6-trifluoromethyl-1H-benzoimidazole

Product 1

HCID 578351994-Bromo-6-trifluoromethyl-2-[4-(3-chloro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole

Sources & evidence

ORD record
ord-3c03c1a5dd714f9ba521edb310fc19bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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