Water → 6-Amino-4-[(3,4-dichloro-6-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]quinazoline

HRID 1132941

Reaction equation

HRID 1132941 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:24][CH2:25][CH2:26][CH2:27][N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[c:18]([N+:21]([O-:22])=[O:23])[cH:19][c:20]23)[c:5]([F:9])[cH:6][c:7]1[Cl:8].[NH2:35][NH2:36].[OH2:34]>>[Cl:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:24][CH2:25][CH2:26][CH2:27][N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[c:18]([NH2:21])[cH:19][c:20]23)[c:5]([F:9])[cH:6][c:7]1[Cl:8]

Participants

4

Reactant 3

HCID 962WaterHCID 9321HydrazineHCID 210800014-[(3,4-Dichloro-6-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-nitroquinazoline

Product 1

HCID 210800076-Amino-4-[(3,4-dichloro-6-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]quinazoline

Sources & evidence

ORD record
ord-ea7bbda9fbb44fa6b57b49831a6551c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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