Dichloromethane → tert-butyl 5-formyl-3,6-dihydro-1(2H)-pyridinecarboxylate

Reaction equation

[Cl:16][CH2:17][Cl:18].[O:19]=[Mn:20]=[O:21].[OH:1][CH2:2][C:3]1=[CH:4][CH2:5][CH2:6][N:7]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:8]1>>[O:1]=[CH:2][C:3]1=[CH:4][CH2:5][CH2:6][N:7]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:8]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 14801Manganese dioxide

HCID 22258851(1-Boc-1,2,5,6-tetrahydropyridin-3-YL)methanol

Product 1

HCID 22258875tert-butyl 5-formyl-3,6-dihydro-1(2H)-pyridinecarboxylate

Sources & evidence

ORD record: ord-e898e41eea1b4f30bc6fa1faca92d5d0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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