Chlorobenzene → N-[2-amino-5-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]pyridine-4-carboxamide

Reaction equation

[C:1]([c:2]1[cH:3][cH:4][n:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH3:10][CH:11]1[CH2:12][C:13](=[O:25])[NH:14][N:15]=[C:16]1[c:17]1[cH:18][c:19]([NH2:24])[c:20]([NH2:23])[cH:21][cH:22]1.[Cl:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[C:1]([c:2]1[cH:3][cH:4][n:5][cH:6][cH:7]1)(=[O:8])[NH:24][c:19]1[cH:18][c:17]([C:16]2=[N:15][NH:14][C:13](=[O:25])[CH2:12][CH:11]2[CH3:10])[cH:22][cH:21][c:20]1[NH2:23]

Participants

Reactant 3

HCID 7964Chlorobenzene

HCID 417436Pyridine-4-carbonyl chloride

HCID 34410526-(3,4-Diaminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Product 1

HCID 13715225N-[2-amino-5-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]pyridine-4-carboxamide

Sources & evidence

ORD record: ord-fe129b2dd2b848dc90ee94ffdebad9b8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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