Ammonia → N-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]thiourea

Reaction equation

[CH3:28][OH:29].[Cl:24][CH2:25][Cl:26].[N:1](=[C:2]=[S:3])[c:4]1[cH:5][cH:6][c:7]([N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)[CH2:14][CH2:15]2)[cH:8][cH:9]1.[NH3:27]>>[NH:1]([C:2](=[S:3])[NH2:27])[c:4]1[cH:5][cH:6][c:7]([N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)[CH2:14][CH2:15]2)[cH:8][cH:9]1

Participants

Reactant 4

HCID 222Ammonia

HCID 887Methanol

HCID 6344Dichloromethane

HCID 155818991-(4-Isothiocyanatophenyl)-4-(4-methoxyphenyl)piperazine

Product 1

HCID 15125461N-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]thiourea

Sources & evidence

ORD record: ord-9bb261bf7e834685adcb6f71ed795c40
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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