2-Methoxy-4-morpholinoaniline → 2-Methoxy-3-[4-(2-methoxy-4-morpholin-4-yl-phenylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-5-methyl-8,9-dihydro-5H-7-oxa-5-aza-benzocyclohepten-6-one

Reaction equation

[CH3:28][O:29][c:30]1[c:31]([NH2:42])[cH:32][cH:33][c:34]([N:36]2[CH2:37][CH2:38][O:39][CH2:40][CH2:41]2)[cH:35]1.[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[cH:14][c:15]3[c:16]([cH:24][c:25]2[O:26][CH3:27])[CH2:17][CH2:18][O:19][C:20](=[O:23])[N:21]3[CH3:22])[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]>>[c:2]1([NH:42][c:31]2[c:30]([O:29][CH3:28])[cH:35][c:34]([N:36]3[CH2:37][CH2:38][O:39][CH2:40][CH2:41]3)[cH:33][cH:32]2)[n:3][c:4]([NH:12][c:13]2[cH:14][c:15]3[c:16]([cH:24][c:25]2[O:26][CH3:27])[CH2:17][CH2:18][O:19][C:20](=[O:23])[N:21]3[CH3:22])[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]