2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2-Fluoro-4-(1-hydroxy-1-methyl ethyl)phenyl]-2-{[6-(2-methoxy-1-morpholin-4-ylethyl)pyridin-2-yl]amino}thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH:8]([CH2:9][O:10][CH3:11])[N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[n:7]1.[NH2:18][c:19]1[s:20][c:21](-[c:27]2[c:28]([F:37])[cH:29][c:30]([C:33]([CH3:34])([CH3:35])[OH:36])[cH:31][cH:32]2)[cH:22][c:23]1[C:24](=[O:25])[NH2:26]>>[c:2]1([NH:18][c:19]2[s:20][c:21](-[c:27]3[c:28]([F:37])[cH:29][c:30]([C:33]([CH3:34])([CH3:35])[OH:36])[cH:31][cH:32]3)[cH:22][c:23]2[C:24](=[O:25])[NH2:26])[cH:3][cH:4][cH:5][c:6]([CH:8]([CH2:9][O:10][CH3:11])[N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c7f35072ee5f463f88d96e0fd5c7b550
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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