Bicarbonate Ion → 2-(6-Methylamino-3-pyridinyl)-1-benzofuran-5-ol

Reaction equation

[B:23]([Br:24])([Br:25])[Br:26].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:8][c:9](-[c:11]3[cH:12][cH:13][c:14]([NH:17][CH3:18])[n:15][cH:16]3)[o:10]2)[cH:19]1.[Cl:20][CH2:21][Cl:22].[Na+:31].[O-:27][C:28]([OH:29])=[O:30].[OH2:32]>>[OH:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:8][c:9](-[c:11]3[cH:12][cH:13][c:14]([NH:17][CH3:18])[n:15][cH:16]3)[o:10]2)[cH:19]1

Participants

Reactant 6

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 962Water

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 250149275-(5-methoxy-1-benzofuran-2-yl)-N-methyl-2-pyridinamine

Product 1

HCID 250148402-(6-Methylamino-3-pyridinyl)-1-benzofuran-5-ol

Sources & evidence

ORD record: ord-70fd8c5f5aee4ae89c4092cc34ed6949
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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