Carbonate Ion → 5-(3-Chloropyridin-4-yl)-6-(3-fluorophenyl)pyrazin-2-amine

HRID 1146736

Reaction equation

HRID 1146736 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([NH2:15])[n:6][c:7]1-[c:8]1[cH:9][c:10]([F:14])[cH:11][cH:12][cH:13]1.[C:26](=[O:27])([O-:28])[O-:29].[Cl:16][c:17]1[cH:18][n:19][cH:20][cH:21][c:22]1[B:23]([OH:24])[OH:25].[Cs+:30].[Cs+:31].[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1>>[c:2]1(-[c:22]2[c:17]([Cl:16])[cH:18][n:19][cH:20][cH:21]2)[n:3][cH:4][c:5]([NH2:15])[n:6][c:7]1-[c:8]1[cH:9][c:10]([F:14])[cH:11][cH:12][cH:13]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 38618773-Chloro-4-pyridineboronic acidHCID 594576145-Bromo-6-(3-fluorophenyl)pyrazin-2-amine

Product 1

HCID 160715405-(3-Chloropyridin-4-yl)-6-(3-fluorophenyl)pyrazin-2-amine

Sources & evidence

ORD record
ord-0d12a34178f1407584ca4a06840ac679
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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