2-Bromo-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide → 4-methyl-2-(2-oxo-3-(4-(trifluoromethoxy)benzyl)pyrrolidin-1-yl)-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide
Reaction equation
[Br:19][c:20]1[s:21][c:22]([C:26](=[O:27])[NH:28][CH2:29][c:30]2[cH:31][n:32][cH:33][cH:34][cH:35]2)[c:23]([CH3:25])[n:24]1.[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][CH:9]2[C:10](=[O:14])[NH:11][CH2:12][CH2:13]2)[cH:15][cH:16]1)([F:17])[F:18]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][CH:9]2[C:10](=[O:14])[N:11]([c:20]3[s:21][c:22]([C:26](=[O:27])[NH:28][CH2:29][c:30]4[cH:31][n:32][cH:33][cH:34][cH:35]4)[c:23]([CH3:25])[n:24]3)[CH2:12][CH2:13]2)[cH:15][cH:16]1)([F:17])[F:18]Participants
3
Sources & evidence
- ORD record
- ord-331156be0ef6486fb510a70e2f1e4128
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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