1-[2-(4-Aminopiperidin-1-yl)ethyl]-7-methoxy-1,4-dihydro-2H-3,1-benzoxazin-2-one → 4-[2-(4-Amino-2-oxopiperidin-1-yl)ethyl]-6-methoxy-2H-1,4-benzoxazin-3(4H)-one

HRID 1151714

Reaction equation

HRID 1151714 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:30]1)[N:8]([CH2:13][CH2:14][N:15]1[C:16](=[O:29])[CH2:17][CH:18]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20]1)[C:9](=[O:12])[CH2:10][O:11]2.[NH2:31][CH:32]1[CH2:33][CH2:34][N:35]([CH2:36][CH2:37][N:38]2[c:39]3[cH:40][c:41]([O:42][CH3:43])[cH:44][cH:45][c:46]3[CH2:47][O:48][C:49]2=[O:50])[CH2:51][CH2:52]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:30]1)[N:8]([CH2:13][CH2:14][N:15]1[C:16](=[O:29])[CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]1)[C:9](=[O:12])[CH2:10][O:11]2

Participants

3

Reactant 2

HCID 667737621-[2-(4-Aminopiperidin-1-yl)ethyl]-7-methoxy-1,4-dihydro-2H-3,1-benzoxazin-2-oneHCID 86642633tert-Butyl {1-[2-(6-methoxy-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)ethyl]-2-oxopiperidin-4-yl}carbamate

Product 1

HCID 667744754-[2-(4-Amino-2-oxopiperidin-1-yl)ethyl]-6-methoxy-2H-1,4-benzoxazin-3(4H)-one

Sources & evidence

ORD record
ord-3a03ff94a87748408c1f12d80d7e8fc7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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