Methyl 2-amino-2-ethylbutanoate → 2-Ethyl-2-[(6-isopropoxy-5-piperidin-1-yl-pyrazine-2-carbonyl)-amino]-butyric acid methyl ester
Reaction equation
[CH3:45][O:46][C:47]([C:48]([CH2:49][CH3:50])([CH2:51][CH3:52])[NH2:53])=[O:54].[CH:26]([CH3:27])([CH3:28])[O:29][c:30]1[c:31]([N:39]2[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]2)[n:32][cH:33][c:34]([C:36](=[O:37])[OH:38])[n:35]1.[OH:1][CH2:2][CH:3]([NH:4][C:5]([c:6]1[cH:7][n:8][c:9]([N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[c:15]([O:16][CH2:17][CH2:18][CH3:19])[n:20]1)=[O:21])[CH2:22][CH:23]([CH3:24])[CH3:25]>>[CH:26]([CH3:27])([CH3:28])[O:29][c:30]1[c:31]([N:39]2[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]2)[n:32][cH:33][c:34]([C:36](=[O:38])[NH:53][C:48]([C:47]([O:46][CH3:45])=[O:54])([CH2:49][CH3:50])[CH2:51][CH3:52])[n:35]1Participants
4
Sources & evidence
- ORD record
- ord-97e44b2bad0b420295ad6590c610160d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)