4-(2-(Pyrrolidin-1-yl)ethoxy)aniline → 5-fluoro-3-[[4-(2-pyrrolidin-1-ylethoxy)anilino]methylidene]-1H-indol-2-one

Participants

Reaction Steps

In a manner similar to that described in Example 231, 4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine (690 mg, 1.2 equiv.) and 5-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 2.79 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (705 mg, 69%).

Provenance & Evidence