4-Quinolinecarboxylic acid → 5-(3,4-Dimethoxyphenyl)-4,4-dimethyl-2-[1-(quinolin-4-ylcarbonyl)piperidin-4-yl]-2,4-dihydro-3H-pyrazol-3-one

HRID 115520

Reaction equation

HRID 115520 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]2=[N:15][N:14]([CH:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[C:13](=[O:22])[C:12]2([CH3:23])[CH3:24])[cH:6][cH:7][c:8]1[O:9][CH3:10].[OH:25][C:26](=[O:27])[c:28]1[cH:29][cH:30][n:31][c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]12>>[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]2=[N:15][N:14]([CH:16]3[CH2:17][CH2:18][N:19]([C:26](=[O:25])[c:28]4[cH:29][cH:30][n:31][c:32]5[cH:33][cH:34][cH:35][cH:36][c:37]45)[CH2:20][CH2:21]3)[C:13](=[O:22])[C:12]2([CH3:23])[CH3:24])[cH:6][cH:7][c:8]1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 102434-Quinolinecarboxylic acidHCID 666164075-(3,4-Dimethoxyphenyl)-4,4-dimethyl-2-piperidin-4-yl-2,4-dihydro-3H-pyrazol-3-one

Product 1

HCID 462049655-(3,4-Dimethoxyphenyl)-4,4-dimethyl-2-[1-(quinolin-4-ylcarbonyl)piperidin-4-yl]-2,4-dihydro-3H-pyrazol-3-one

Sources & evidence

ORD record
ord-00580ba280cf4717a945a4b89b4bea57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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