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Aniline → HCID 178419090, compound

HRID 11554
Notes
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Reaction equation

HRID 11554 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][C:5](=[O:11])[NH:6]2.N1C2C(=CC=CC=2)C[C:13]1=O.[N:22]1([CH2:28][CH2:29][CH2:30][NH:31][C:32]2[CH:37]=[CH:36][C:35]([NH2:38])=[CH:34][CH:33]=2)[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1.NC1C=CC=CC=1>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4](=[CH:13][NH:38][C:35]1[CH:36]=[CH:37][C:32]([NH:31][CH2:30][CH2:29][CH2:28][N:22]3[CH2:27][CH2:26][O:25][CH2:24][CH2:23]3)=[CH:33][CH:34]=1)[C:5](=[O:11])[NH:6]2
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 6115AnilineHCID 321710OxindoleHCID 125793824-Methyl-1,3-dihydro-2H-indol-2-oneHCID 21974739N1-(3-Morpholinopropyl)benzene-1,4-diamine

Product 1

HCID 178419090HCID 178419090, compound

Procedure

The named compound is prepared by substituting 4-methyl-1,3-dihydro-indol-2-one for the 1,3-dihydro-indol-2-one and N-(3-morpholin-4-yl-propyl)-benzene-1,4-diamine (used for the preparation of Example 290) for aniline in the reaction of Example 1.

Workup

  1. customThe named compound is prepared
  2. customin the reaction of Example 1

Sources & evidence

ORD record
ord-5e9e9595f9b24f91af653c3b48e4f759
Source dataset
uspto-grants-2006_08
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US07098236B2

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes