Pivaloyl chloride → 1-Methyl-4-phenyl-4-(4-pivaloylaminophenoxy)piperidine

HRID 1156036

Reaction equation

HRID 1156036 reaction equation
[NH2:1][C:2]1[CH:21]=[CH:20][C:5]([O:6][C:7]2([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]2)=[CH:4][CH:3]=1.[C:22](Cl)(=[O:27])[C:23]([CH3:26])([CH3:25])[CH3:24]>>[CH3:13][N:10]1[CH2:9][CH2:8][C:7]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)([O:6][C:5]2[CH:20]=[CH:21][C:2]([NH:1][C:22](=[O:27])[C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:3][CH:4]=2)[CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 62493Pivaloyl chlorideHCID 3060392Piperidine, 4-(p-aminophenoxy)-1-methyl-4-phenyl-

Product 1

HCID 205365801-Methyl-4-phenyl-4-(4-pivaloylaminophenoxy)piperidine

Procedure

from 4-(4-aminophenoxy)-1-methyl-4-phenylpiperidine and pivaloyl chloride.

Sources & evidence

ORD record
ord-9b375cd86a634dbbb4e485699b82605b
Source dataset
uspto-grants-1982_06
Patent number
US04333942

Linked notes

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