5-Methoxypyridine-3-boronic Acid → [2,6-Difluoro-4-(5-methoxy-3-pyridinyl)phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone
Reaction equation
[Br:12][c:13]1[cH:14][c:15]([F:33])[c:16]([C:20](=[O:21])[N:22]2[CH:23]([CH2:27][N:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[CH2:24][CH2:25][CH2:26]2)[c:17]([F:19])[cH:18]1.[CH3:1][O:2][c:3]1[cH:4][n:5][cH:6][c:7]([B:9]([OH:10])[OH:11])[cH:8]1>>[CH3:1][O:2][c:3]1[cH:4][n:5][cH:6][c:7](-[c:13]2[cH:14][c:15]([F:33])[c:16]([C:20](=[O:21])[N:22]3[CH:23]([CH2:27][N:28]4[CH2:29][CH2:30][CH2:31][CH2:32]4)[CH2:24][CH2:25][CH2:26]3)[c:17]([F:19])[cH:18]2)[cH:8]1Participants
3
Sources & evidence
- ORD record
- ord-b40f34ac4f32413391eb5b0a08df7a72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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